Self-Assembly Peptides-a Review
- 1 Department of Chemistry, Faculty of Science, Federal University Oye-Ekiti, Nigeria
- 2 Department of Chemical Engineering, College of Engineering, Lagos State University of Science and Technology, Nigeria
- 3 Department of Chemical Sciences, Faculty of Science, Niger Delta University, Nigeria
- 4 Department of Chemistry, Faculty of Applied and Computer Sciences, Vaal University of Technology, South Africa
- 5 School of Chemistry and Physics, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Westville Durban 4000, KwaZulu-Natal, South Africa
Abstract
Self-assembling of peptides is a spontaneous process by which peptides are self-organized to form well-ordered structures by intramolecular and intermolecular interactions.This process is controlled by the balance of the forces (attractive andrepulsive) within the peptide molecules. Notable methods used for the synthesis of self-assembly peptides are solid-phase synthesis, liquid-phase synthesis,recombinant technology, and the use of external fields. The self-assembled nanostructure-based peptides offer remarkable advantages; such as mild synthesis conditions, relatively simple functionalization, fast synthesis, and low cost, resulting in theirremarkable potential for use in biosensors, imaging tools, antimicrobialagents, drug delivery systems, bioelectronics, tissue reparation. Herein, wepresent the origin of self-assembled peptides, synthesis of novel materials produced through self-assembly of peptides, structural elucidation, applications, recent trends, and the future outlook of self-assembly peptides.
DOI: https://doi.org/10.3844/ojbsci.2022.309.322
Copyright: © 2022 Olushola Sunday Ayanda, Olusola Solomon Amodu, Cyprian Yameso Abasi, Michael John Klink, Simphiwe Maurice Nelana and Olatunde Stephen Olatunji. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Biomolecules
- Self-Assembled Peptide
- Nanostructure
- Nanotechnology