Non-Specific Interstitial Pneumonia Overlapping Tuberculosis: A Diagnostic Challenge in Elderly
- 1 All India Institute of Medical Sciences, India
Abstract
Non-Specific Interstitial Pneumonia (NSIP) is linked to numerous etiologies, including connective tissue diseases, certain drugs, HIV and idiopathic causes. We present a case of an 82-year-old woman with subacute onset shortness of breath as the presenting feature of Non-specific interstitial pneumonia. Chest imaging demonstrated bilateral infiltrates and tentatively diagnosed as NSIP and started on Tyrosine kinase inhibitor - Nintedanib. But she worsened symptomatically and on further evaluation, Mycobacterium tuberculosis had been detected in her Sputum. Anti-tuberculous therapy and Tyrosine Kinase Inhibitor (TKI) resolved her pulmonary symptoms to an extent and she was discharged on Long term oxygen therapy. In this case, we encountered a Tuberculosis (TB) case with NSIP where NSIP could overlap the diagnosis of TB and we should have a strong suspicion of TB in geriatric people.
DOI: https://doi.org/10.3844/ajidsp.2021.161.164
Copyright: © 2021 Pradeep Chakaravarthy, Divanshee Sharma, Manjunath Totaganti, Jithesh G, Mukesh Bairwa and Ravikant. This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Non-Specific Interstitial Pneumonia
- Tuberculosis
- Rheumatoid Arthritis
- Osteoarthritis
- Steroids
- Geriatric Population